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DietlandlExercise are not the OnlylFactors Related tolWeightlGain andlObesity

What Hollywood Stars have known for years has now been validated with new evidence from scientific research conducted at Baylor College of Medicine, that suggests as we getlolder, we getlfatter 1. Additionally other research has shown that stubbornlbellylfatlandlobesity may actually be caused by the oxidative stress that is generated as a result of toxins and free radicals produced by thelbody following chronic consumption oflsugars andlcarbohydrates 2.Research also suggests that uncontrolled buildup of these toxins and free radicals (called oxidative stress), leads to a condition where thelbody stores morelfat and uses lesslcalories makinglweightlloss much more difficult andlweightlgain much easier 2. Maybe some of you have experienced the frustration of cuttinglcalories and starting tolexercise, only to see the scale stare back at you each day not moving or even moving the wrong direction.

For many of us, including myself, the battleloflthelbulge has been a lifetime battle that I have been losing over the years. What I’ve recently learned is that the complex biochemical process that governs how muchlfat we store, how much we burn, and howlhungry we are malfunctions under heavy toxic load, making it easier to storelfat 2. When we try to startlexercising and change ourldiets, all we find is frustration because ourlbody’s natural processes aren’t functioning correctly anymore due to this high level of toxicity.

In addition to the toxic load, free radicals, and oxidative stress that is created over time by eating the wronglfoods mentioned above, artificiallsweeteners,ldietlproducts, andldiet pills all add additional toxins to the body, just pushing thelbody further out of balance and making it easier to store morelfat.

Luckily for for me and now for you, I accidentally stumbled onto a solution that helps break this cycle. This is my story of how I discovered thatlmetabolic rate andlfat storage are affected by the levels of oxidative stress 2 and free radicals and toxins left unchecked develop into this state of oxidative stress.

My Journey with Nano Glutathione

I initially started taking Nano Glutathione to improve my overall health and well being. Glutathione has been featured in over 89,000 studies and low glutathione has been linked to variousldiseaseslincludinglobesity,ldiabetes, heartldisease, lcancer, Alzheimer’s,lParkinson’s,lprematurelaging,lAutism, eczemalandlpsoriasis, rheumatoidlarthritis, autoimmuneldiseases, osteoporosis,lseizures and more 3-11.

I did not start taking Nano Glutathione with any specific expectation on what it might do for me, but once I realized there were some changes in mylbody, I decided to research the relationship of glutathione and this complex set of hormones that controllmetabolism,lfat storage, andlhunger in thelbody which I’ll come back to a little later, but first my incredible story.

Almost immediately after I startd taking Nano Glutathione, I noticed an increase in energy. My hair dresser even commented on the fact that I had noticeably less greylhair 12 on the sides of my head where it had been slowly taking over. My skin on my face was clearer and less puffy 13. My blood pressure went down about 10 points 14. In general I felt great.

I have a regular gym schedule but had been stuck for some time atlalweight plateau. I wouldn’t say I amlfat, but I’m notlskinny either. I’ve typically always carried “alfewlextralpounds” even though I am healthy enough. Additional effort tolexercise harder or to maintain more discipline with myldiet didn’t really ever seem to produce much in the way oflfat loss and so I had just kind of resigned myself to the fact that having a few extralpounds is just what happens as youlage.

I continued with my normal gymlschedule and my normalldiet which isn’t too heavily laden with unhealthylfoods, but I wouldn’t classify as overly healthy either. During the first few weeks I wasn’t really paying that close of attention to mylbody and wasn’t really expecting any changes. One morning my partner looked at me, and said, “Baby, I think you’re finally making progress with thatldietlandlexercise routine.” This prompted me to begin my research into the role glutathione plays in thelbody.

I spent hours researching the complexities of how oxidative stress affects the metabolism and can causelweightlgain 2. Once I’d summarized my research, I shared it with Nanoceutical Solutions, the company that makes Nano Glutathione and was honored with a request by the company to share this blog article with their facebook followers and community as there are millions of people in the US struggling with the same issues of just not being able to make any progress in spite of significant changes toldietlandlexercise.

EDITOR’S NOTE: The results presented are remarkable and since there is strong evidence showing the connection to leptin and insulin resistance, inflammation and oxidative stress, and low glutathione levels, Nano Glutathione may benefit a large number of people including those struggling with the conditions above, but people’s individual results will vary and the results above may not be typical.

Leptin,lInsulin,lGlutathione, andlWeightlLoss

The mechanisms of how toxins and oxidative stress contribute tolweightlgain and prohibitlweightlloss are complex, and have only recently been brought to light through scientific research. The key players arelinsulin,lleptin, oxidative stress, and inflammation.

Insulinlis a hormone produced in the pancreas, and is responsible for regulating bloodlsugar and various hormones in thelbody.lInsulinlis the key that unlocks the cell, allowing the cell to absorb glucose, which comes fromlcarbohydrates in yourlfood such aslsugar andlstarches (bread,lpasta,lpotatolchips, etc). Thelglucose is then either used as energy, or converted intolfat. The morelcarbohydrates in yourlbody, the morelinsulin yourlbody will create.

Leptinlis a hormone secreted bylfat cells.lLeptinlprovides feedback to your brain regarding the amount oflfat stored in yourlbody, and regulates your brain’s sense of beinglhungry. The morelfat in yourlbody, the morelleptin yourlbody will create. Also, elevatedlinsulin levels will cause the secretion of morelleptin.

Leptinlcauses oxidative stress in thelbody, which results in inflammation. This is a normal part of thelmetabolic process. As mentioned earlier, thelbody’s ability to address oxidative stress is dependent upon glutathione reserves, which are limited and decrease with age and with consumption and exposure to toxins.

Where things get out of control is during the process oflovereating, and especiallylovereating simplelcarbohydrates andlsugars.lOverconsumptionloflfood, even temporarily, causes an inflammatory state of oxidative stress in your cells that leads tolinsulin resistance, becauselinsulin cannot easily pass through a cell when it is inflamed. Yourlbody’s response to this is to create morelinsulin, which forces even morelleptin to be secreted.

The brain becomes desensitized tolleptin easily, driving ongoingloverconsumptionloflfood because the “stopleating” signal is not being received properly.lOvereatingloflcarbohydrates is especially dangerous to this process due to the relationship oflinsulin andlleptin. Carbslincreaselinsulin,linsulinlincreaseslleptinl-lovereating increaseslleptin, and all of this increases oxidative stress and inflammation which depletes your glutathione. To make matters worse, yourlbody’s glutathione production is reduced under high levels of oxidative stress, meaning there is less glutathione to clean out the increasing amounts of toxins and free radicals 14. You can see how this creates a nasty feedback loop that can be impossible to escape from when thelbody cannot handle the toxins and free radicals. It leads to rapidlweightlgain,lmetabolicldisorder,ldiabetes,land potentially numerous otherldiseases 15.

So how do you get out of this trap? The first step is to help yourlbody reduce the inflammation and oxidative stress, while at the same time adjusting yourldiet. In my case, I had already made adjustments to my diet and had also added moderatelexercise to my daily routine, but mylbody wasn’t responding to these changes because I had not addressed the oxidative stress and inflammation adequately. By adding Nano Glutathione to what I was already doing, I was addressing the oxidative stress in mylbody and working to clear the free radicals and toxins.

*results may vary

What It All Means

Even with a background in science, this is very confusing stuff and the relationships of all these hormones in thelbody are just now starting to be understood by the experts. But one thing is becoming increasingly clear. The relationship of thelmetabolism andlfatlstorage is not just a simple relationship of how manylcalories youleat and how manylcalories you should be burning. Oxidative stress and low glutathione can slow the amount oflcalories you burn and increase the amount oflcalories you store, makinglweightlgain possible even when cuttinglcalories and increasinglexercise.

Reducing inflammation and oxidative stress by increasing glutathione levels has been shown in recent research to assist thelbody in rebalancing its natural processes including thelmetaboliclrate to optimal levels 16. This means for someone like me who was making the effort toleat lesslcarbohydrates, fewerlcalories andlexercise more, that by reducing oxidative stress andlinflammation while also increasing glutathione levels, it’s possible to see improvements where they weren’t possible before.

What is Glutathione?

Glutathione is widely accepted by the medical community as a primary antioxidant and intracellular detoxification agent in thelbody.

The main reason you probably haven’t heard of glutathione, is that until recently direct oral supplementation was ineffective because glutathione is destroyed in the digestive tract before being absorbed 16. Consequently, increasing glutathione levels has been largely limited to expensive and painful IV treatments (over $1000 a treatment), or supplementing with oral glutathione precursors such as whey protein, NAC, cysteine, and glycine among others.

As I mentioned earlier, low glutathione levels have been linked to a large number ofldiseases includinglobesity,ldiabetes,lheartldisease, cancer,lAlzheimer’s,lParkinson’s,lprematurelaging,lAutism,leczemalandlpsoriasis,lrheumatoidlarthritis,lautoimmuneldiseases,losteoporosis,lseizureslandlmore. In addition to low glutathione being linked to variousldiseases, maintaining optimal glutathione levels has also been linked tollongevity. In a study over 5 years on healthy women between the ages of 60 and 103 found that all subjects had very high levels of glutathione in their bloodstream 17.

*results may vary

Why is Nano Glutathione Different?

I was one of the early recipients of this new breakthrough supplement from Nanoceutical Solutions called Nano Glutathione. This supplement uses revolutionary technology to dramatically reduce the particle size of the glutathione to 1/20,000 of normal glutathione causing an amazing absorption rate of over 80% within seconds of oral ingestion 18. This allows these molecules to pass straight through the lining of the mouth and directly into the bloodstream. By comparison, a study by Bastyr University Research Institute and the University of Washington on the effect of taking traditional oral glutathione found no significant changes in the biomarkers of oxidative stress, including glutathione levels 19.

Time (in Seconds) % of Glutathione Delivered to the Bloodstream
40s 54%
60s 80%
90s 83%

Supplementing With Nano Glutathione

Nano Glutathione was made available to select participants including myself over the last few months ahead of Nanoceutical Solutions selling the product publicly. The accounts below are a few of those participant’s reports following taking Nano Glutathione.

Brad, a 43 year old from Houston, TX had been diagnosed with elevated liver enzymes and borderline high blood pressure. He received Nano Glutathione from Nanoceutical Solutions and within a month his liver enzymes had returned to normal and his bloodlpressure had returned to the normal range. He reported back his results to the company and purchased additional bottles in order to maintain optimal wellness and keep hislbody free of oxidation. During the next 4 weeks after receiving his new supply of Nano Glutathione he experienced significant changes in hislbody without changing hisldiet orlexercise routine.

EDITOR’S NOTE: The results presented are remarkable and since there is strong evidence showing the connection to leptin and insulin resistance, inflammation and oxidative stress, and low glutathione levels, Nano Glutathione may benefit a large number of people including those struggling with the conditions above, but people’s individual results will vary and the results above may not be typical.

Barbara, age 73 and Cliff, age 75 from Hillsboro, have been taking Nano Glutathione for the last month before this article was written. Barbara started taking Nano Glutathione with the hope it would relieve some of the memory issues she was having as she’d read thatldementia andlAlzheimer’s had been linked to oxidative stress. After just a few weeks, she reported back that her memory was much better, that she was achieving new high scores almost daily on her favorite game Word With Friends and that she was having a much easier time remembering the things she needed to do without having to retrace her steps all the time. Additionally she reported that her jointlpain had subsided significantly and most recently she reported that she had she and Cliff had experienced positivelbody changes without adding or changing anything in their routine orldiet but adding Nano Glutathione.

EDITOR’S NOTE: The results presented are remarkable and since there is strong evidence showing the connection to leptin and insulin resistance, inflammation and oxidative stress, and low glutathione levels, Nano Glutathione may benefit a large number of people including those struggling with the conditions above, but people’s individual results will vary and the results above may not be typical.

Try it For Yourself

Brad, Barbara, Cliff and I all received our Nano Glutathione direct from the manufacturer Nanoceutical Solutions. Nanoceutical Solutions manufactures their Glutathione in San Antonio, Texas in an FDA registered facility and they manufacture all their supplements with pharmaceutical grade ingredients. The company is a also a member of the BBB and they stand behind their products by offering a 90ldaylmoneylbacklguarantee on first time purchases, and al30ldaylguarantee on any repeat purchases. You can try it for yourself by clicking this link or the link below. And please come back and let us know how it worked. We’d love to share your experience. And as with all supplements, everyone is different and results may vary.

* Offer only valid for new customers. Participation may require joining a subscription program in which you will be billed until you cancel. Valid only on 5 bottle supply. Not valid on single or 3 month supply. See the terms and conditions on the website for details.

Representations regarding the efficacy and safety of Nano Glutathione have not been evaluated by thelFood and Drug Administration. The FDA only evaluateslfoods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure anyldisease. It is recommended that users follow a strictldiet andlexercise regimen to achievelweightlloss results. These products are not intended to diagnose, prevent, treat, or cure anyldisease. Click below to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of glutathione based on the expertise of relevant professionals.

  1. Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione
    Dan Nguyen-Susan Samson-Vasumathi Reddy-Erica Gonzalez-Rajagopal Sekhar - http://onlinelibrary.wiley.com/doi/10.1111/acel.12073/abstract
  2. Effect of Leptin and Oxidative Stress in the Blood of Obese Individuals
    Shaimaa Ahmed-Firas Maher-Nazar Naji - https://www.omicsonline.org/open-access/effect-of-leptin-and-oxidative-stress-in-the-blood-of-obese-individuals-2161-1009-1000288.php?aid=80393&view=mobile
  3. Oxidative Stress and Obesity: The Chicken or the Egg?
    Annayya Aroor-Vincent DeMarco - http://diabetes.diabetesjournals.org/content/63/7/2216
  4. Effect of Increasing Glutathione With Cysteine and Glycine Supplementation on Mitochondrial Fuel Oxidation, Insulin Sensitivity, and Body Composition in Older HIV-Infected Patients
    Dan Nguyen-Jean Hsu-Farook Jahoor-Rajagopal Sekhar - http://press.endocrine.org/doi/abs/10.1210/jc.2013-2376
  5. lutathione dysregulation and the etiology and progression of human diseases
    Nazzareno Ballatori-Suzanne Krance-Sylvia Notenboom-Shujie Shi-Kim Tieu-Christine Hammond - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756154/
  6. The emerging role of glutathione in Alzheimer's disease.
    S Saharan-P Mandal - https://www.ncbi.nlm.nih.gov/pubmed/24496077
  7. Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine
    Rajagopal Sekhar-Siripoom McKay-Sanjeet Patel-Anuradha Guthikonda-Vasumathi Reddy-Ashok Balasubramanyam-Farook Jahoor - http://care.diabetesjournals.org/content/34/1/162
  8. Serum antioxidants and nitric oxide levels in fibromyalgia: a controlled study.
    O Sendur-Y Turan-E Tastaban-C Yenisey-M Serter - http://www.ncbi.nlm.nih.gov/pubmed/18853166
  9. Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction.
    W Dröge-E Holm - http://www.ncbi.nlm.nih.gov/pubmed/9367343
  10. Effect of liver cirrhosis and age on the glutathione concentration in the plasma, erythrocytes, and gastric mucosa of man.
    C Loguercio-D Taranto-L Vitale-F Beneduce-C Del - http://www.ncbi.nlm.nih.gov/pubmed/8720922
  11. The glutathione defense system in the pathogenesis of rheumatoid arthritis.
    M Hassan-R Hadi-Z Al-Rawi-V Padron-S Stohs - http://www.ncbi.nlm.nih.gov/pubmed/11180282
  12. Oxidative Stress in Ageing of Hair
    Ralph Trüeb - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929555/
  13. Skin anti-aging strategies
    Ruta Ganceviciene-Aikaterini Liakou-Athanasios Theodoridis-Evgenia Makrantonaki-Christos Zouboulis - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583892/
  14. Oxidative stress and hypertension: Possibility of hypertension therapy with antioxidants
    Azar Baradaran-Hamid Nasri-Mahmoud Rafieian-Kopaei - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115353/
  15. Glutathione: a key player in autoimmunity.
    C Perricone-C De-R Perricone - http://www.ncbi.nlm.nih.gov/pubmed/19393193
  16. Glutathione Depletion/Methylation Blockades in Chronic Fatigue Syndrome
    2012 4 - http://phoenixrising.me/research-2/glutathione-depletionmethylation-blockades-in-chronic-fatigue-syndrome/glutathione-depletion-methylation-cycle-block-a-hypothesis-for-the-pathogenesis-of-chronic-fatigue-syndrome-by-richard-a-van-konynenbury-ph-d
  17. High blood glutathione levels accompany excellent physical and mental health in women ages 60 to 103 years.
    C Lang-B Mills-H Lang-M Liu-W Usui-J Richie-W Mastropaolo-S Murrell - https://www.ncbi.nlm.nih.gov/pubmed/12486409
  18. Nano Glutathione Diffusion Study Results
    https://www.nanoceuticalsolutions.com/wp-content/uploads/2016/06/Nano-Glutathione-Drug-Diffususion-Study-Results.pdf
  19. Effects of Oral Glutathione Supplementation on Systemic Oxidative Stress Biomarkers in Human Volunteers
    Jason Allen-Ryan Bradley - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162377/
  20. Correcting glutathione deficiency improves impaired mitochondrial fat burning, insulin resistance in aging
    Dipali Pathak713-798-4710Houston, TX - Apr 2, 2013 Tweet share- Dipali Pathak713-798-4710Houston, TX - Apr 2, 2013 - https://www.bcm.edu/news/geriatrics/glutathione-deficiency-fat-insulin-aging

Sources


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